Lysosomal dysfunction and glycosphingolipid dysregulation in rare and common neurodegenerative diseases

Lysosomal dysfunction and glycosphingolipid dysregulation in rare and common neurodegenerative diseases

<p>Historically, the rare early-onset neurodegenerative lysosomal storage disorders (LSDs) have been studied as discrete metabolic diseases in their own right. However, in recent years links with more common late-onset neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS...

Полное описание

Библиографические подробности
Главный автор:	Huebecker, M
Другие авторы:	Platt, F
Формат:	Диссертация
Язык:	English
Опубликовано:	2019
Предметы:	Molecular biology Biochemistry

Схожие документы

Glycosphingolipid dysregulation and lysosomal dysfunction in motor neuron disease
по: da Silva Santos, CS
Опубликовано: (2021)

Early onset effects of single substrate accumulation recapitulate major features of LSD in patient-derived lysosomes
по: Gianluca Scerra, и др.
Опубликовано: (2021-07-01)

Mucosal absorption of therapeutic peptides by harnessing the endogenous sorting of glycosphingolipids
по: Garcia-Castillo, Maria Daniela, и др.
Опубликовано: (2020)

Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders
по: Jen-Jie Lee, и др.
Опубликовано: (2024-04-01)

Modern experimental biochemistry /
по: 324400 Boyer, Rodney F.
Опубликовано: (1993)

Biochemistry and molecular biology compendium /
по: 340867 Lundblad, Roger L.
Опубликовано: (c200)

Modern experimental biochemistry /
по: 324400 Boyer, Rodney F.
Опубликовано: (2000)

circGlis3 promotes β-cell dysfunction by binding to heterogeneous nuclear ribonucleoprotein F and encoding Glis3-348aa protein
по: Li Xiong, и др.
Опубликовано: (2024-01-01)

Molecular and cellular biochemistry : an international journal for chemical biology in health and disease
Опубликовано: (1973)

Harper's illustrated biochemistry /
по: Murray, Robert K, и др.
Опубликовано: (2003)

Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome
по: Natalie M. Hendrikse, и др.
Опубликовано: (2021-03-01)

Learned features of antibody-antigen binding affinity
по: Miller, Nathaniel L., и др.
Опубликовано: (2023)

Studying the role of protein deamidation in neurodegenerative disease in proteome-wide scale
по: Ang, Yi Lin
Опубликовано: (2014)

Molecular motors /
по: Schliwa, M. (Manfred), 1945-
Опубликовано: (2003)

Evolutional insights into the interaction between Rab7 and RILP in lysosome motility
по: Gaofeng Cui, и др.
Опубликовано: (2023-07-01)

Principles and techniques of biochemistry and molecular biology /
по: Wilson, Keith, 1936-, и др.
Опубликовано: (2010)

Principles and techniques of biochemistry and molecular biology /
по: Wilson, Keith, 1936-, и др.
Опубликовано: (2005)

Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
по: Cuiyan Xin, и др.
Опубликовано: (2021-10-01)

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel
по: Si Min Zhang, и др.
Опубликовано: (2024-02-01)

Studying the function and regulation of non-coding transcription in fission yeast by the exosome complex
по: Shah, S
Опубликовано: (2014)

UXT oligomerization is essential for its role as an autophagy adaptor
по: Min Ji Yoon, и др.
Опубликовано: (2025-03-01)

HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury
по: Ning Li, и др.
Опубликовано: (2023-07-01)

Oxford dictionary of biochemistry and molecular biology /
по: Cammack, Richard
Опубликовано: (2006)

Chemico-biological interactions
Опубликовано: (1969)

Encyclopaedia of tools and techniques in biochemistry and molecular biology /
по: Crasta, Darrel
Опубликовано: (2012)

European journal of biochemistry [Compact Disc]
Опубликовано: (1992)

Biochemistry and molecular biology of plants [electronic resource] /
по: 265742 Buchanan, Bob B.
Опубликовано: (2001)

CRC handbook of biochemistry and molecular biology/
по: Fasman, Gerald D.
Опубликовано: (1975)

Biochemistry and molecular biology /
по: 306910 Elliott, William H., и др.
Опубликовано: (2009)

Dictionary of biochemistry and molecular biology /
по: 314158 Stenesh, Jochanan
Опубликовано: (1989)

Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.
по: Jeyakumar, M, и др.
Опубликовано: (2002)

Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis
по: Saw, Wuan-Geok, и др.
Опубликовано: (2020)

Microproteins: Overlooked regulators of physiology and disease
по: Keira R. Hassel, и др.
Опубликовано: (2023-06-01)

The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling
по: Emmanuel Laplantine, и др.
Опубликовано: (2022-10-01)

Lysosomal-endolysomal dysfunction and neurodegenerative diseases
по: Matthew E. Gegg, и др.
Опубликовано: (2022-10-01)

Identification of the interacting partners of a lysosomal membrane protein in living cells by BioID technique
по: Dat Nguyen-Tien, и др.
Опубликовано: (2022-06-01)

Dysregulated dopamine metabolism in LRRK2 mutants
по: Chia, Xin Tian
Опубликовано: (2015)

Mathematical modelling of cell cycle network motifs controlling M-Phase progression
по: Hopkins, M
Опубликовано: (2018)

Editorial: Mitochondrial and lysosomal dysfunction in neurodegenerative diseases: Molecular mechanisms and therapeutic strategies
по: Chen Xiang, и др.
Опубликовано: (2022-10-01)

PIAS-family proteins negatively regulate Glis3 transactivation function through SUMO modification in pancreatic β cells
по: Tyler M. Hoard, и др.
Опубликовано: (2018-07-01)