Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II

Influenza A viruses, causing seasonal epidemics and occasional pandemics, rely on interactions with host proteins for their RNA genome transcription and replication. The viral RNA polymerase utilizes host RNA polymerase II (Pol II) and interacts with the serine 5 phosphorylated (pS5) C-terminal doma...

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Main Authors: Keown, J, Baazaoui, A, Sebesta, M, Stefl, R, Carrique, L, Fodor, E, Grimes, JM
格式: Journal article
语言:English
出版: American Society for Microbiology 2024

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