Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II

Influenza A viruses, causing seasonal epidemics and occasional pandemics, rely on interactions with host proteins for their RNA genome transcription and replication. The viral RNA polymerase utilizes host RNA polymerase II (Pol II) and interacts with the serine 5 phosphorylated (pS5) C-terminal doma...

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Detalhes bibliográficos
Main Authors: Keown, J, Baazaoui, A, Sebesta, M, Stefl, R, Carrique, L, Fodor, E, Grimes, JM
Formato: Journal article
Idioma:English
Publicado em: American Society for Microbiology 2024