Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection.

Hepatitis C virus (HCV) becomes persistent in the majority of infected individuals. In doing so, the virus evades host adaptive immune responses, although the mechanisms responsible in this evasion are not clear. Several groups have demonstrated weak or absent HCV-specific CD4+ T cell responses duri...

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Bibliographic Details
Main Authors: Semmo, N, Day, C, Ward, S, Lucas, M, Harcourt, G, Loughry, A, Klenerman, P
Format: Journal article
Language:English
Published: 2005