Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains.

Staphylococcus aureus can adhere to and invade endothelial cells by binding to the human protein fibronectin (Fn). FnBPA and FnBPB, cell wall-attached proteins from S. aureus, have multiple, intrinsically disordered, high-affinity binding repeats (FnBRs) for Fn. Here, 30 years after the first report...

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Bibliographic Details
Main Authors: Bingham, R, Rudiño-Piñera, E, Meenan, N, Schwarz-Linek, U, Turkenburg, J, Höök, M, Garman, E, Potts, JR
Format: Journal article
Language:English
Published: 2008