The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis

Recent advances in the understanding of the genetics of type 2 diabetes (T2D) susceptibility have focused attention on the regulation of transcriptional activity within the pancreatic beta-cell. MicroRNAs (miRNAs) represent an important component of regulatory control, and have proven roles in the d...

Bibliográfalaš dieđut
Váldodahkkit:	Van De Bunt, M, Gaulton, K, Parts, L, Moran, I, Johnson, P, Lindgren, C, Ferrer, J, Gloyn, A, McCarthy, M
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	Public Library of Science 2013

Geahča maid

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.
Dahkki: Martijn van de Bunt, et al.
Almmustuhtton: (2013-01-01)

Insights into β-cell biology and type 2 diabetes pathogenesis from studies of the islet transcriptome
Dahkki: Van De Bunt, M, et al.
Almmustuhtton: (2014)

Human pancreatic islet miRNA-mRNA networks of altered miRNAs due to glycemic status
Dahkki: Alexandros Karagiannopoulos, et al.
Almmustuhtton: (2022-04-01)

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Dahkki: Thurner, M, et al.
Almmustuhtton: (2018)

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development.
Dahkki: Wigard P Kloosterman, et al.
Almmustuhtton: (2007-08-01)

Computational and Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy
Dahkki: Nalini Venkatesan, et al.
Almmustuhtton: (2015-01-01)

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.
Dahkki: Pasquali, L, et al.
Almmustuhtton: (2014)

Computational and in vitro Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy
Dahkki: Nalini Venkatesan, et al.
Almmustuhtton: (2015-05-01)

Expression of Concern: Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development.
Dahkki: PLOS Biology Editors
Almmustuhtton: (2022-04-01)

The role of lncRNA and miRNA in the pathogenesis of renal fibrosis
Dahkki: Liang CHANG, et al.
Almmustuhtton: (2023-04-01)

The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Dahkki: Łukasz Pulik, et al.
Almmustuhtton: (2022-12-01)

Genetic regulation of RNA splicing in human pancreatic islets
Dahkki: Goutham Atla, et al.
Almmustuhtton: (2022-09-01)

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
Dahkki: Pasquali, L, et al.
Almmustuhtton: (2014)

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Dahkki: Matthias Thurner, et al.
Almmustuhtton: (2018-02-01)

miRNA-Mediated Immune Regulation in Islet Autoimmunity and Type 1 Diabetes
Dahkki: Martin G. Scherm, et al.
Almmustuhtton: (2020-11-01)

miRNA expression profile in rats correlates with type-2-diabetes phenotype
Dahkki: Herrera, B, et al.
Almmustuhtton: (2008)

Gene expression analysis demonstrates presence of a non-coding RNA (ANRIL) in human islets and FACs sorted beta cells which has a potential regulatory role on CDKN2B expression
Dahkki: Pal, A, et al.
Almmustuhtton: (2009)

Mechanisms of genome regulation in human islets and their role in the pathogenesis of type 2 diabetes
Dahkki: van de Bunt, G, et al.
Almmustuhtton: (2014)

ZIKV Infection and miRNA Network in Pathogenesis and Immune Response
Dahkki: Carolina Manganeli Polonio, et al.
Almmustuhtton: (2021-10-01)

MiR-184 expression is regulated by AMPK in pancreatic islets
Dahkki: Martinez-Sanchez, A, et al.
Almmustuhtton: (2017)

CircRNA-miRNA-VEGFA: an important pathway to regulate cancer pathogenesis
Dahkki: Lei Zhang, et al.
Almmustuhtton: (2023-05-01)

Differences between global miRNA expression profiles in diabetic and normoglycaemic rats
Dahkki: Herrera, B, et al.
Almmustuhtton: (2008)

Clinical and biological significance of circulating miRNAs in chronic pancreatitis patients undergoing total pancreatectomy with islet autotransplantation
Dahkki: Srividya Vasu, et al.
Almmustuhtton: (2023-10-01)

Major miRNA Involved in Insulin Secretion and Production in Beta-Cells
Dahkki: Aghaei M, et al.
Almmustuhtton: (2020-03-01)

The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy.
Dahkki: Sibley, C, et al.
Almmustuhtton: (2011)

The miRNA pathway in neurological and skeletal muscle disease: Implications for pathogenesis and therapy
Dahkki: Sibley, C, et al.
Almmustuhtton: (2011)

Association of Chromosomal Translocation and MiRNA Expression with The Pathogenesis of Multiple Myeloma
Dahkki: Najmaldin Saki, et al.
Almmustuhtton: (2014-06-01)

miRNA Landscape in Pathogenesis and Treatment of Vogt–Koyanagi–Harada Disease
Dahkki: Fabian Vega-Tapia, et al.
Almmustuhtton: (2021-05-01)

Altered Purkinje cell miRNA expression and SCA1 pathogenesis
Dahkki: Edgardo Rodriguez-Lebron, et al.
Almmustuhtton: (2013-06-01)

Regulation of miRNA content. Part 1. Editing miRNA. Тailing miRNA
Dahkki: A.E. Abaturov, et al.
Almmustuhtton: (2021-06-01)

Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model
Dahkki: van de Bunt, M, et al.
Almmustuhtton: (2016)

Real-time monitoring of miRNA function in pancreatic cell lines using recombinant AAV-based miRNA Asensors.
Dahkki: Jing Chen, et al.
Almmustuhtton: (2013-01-01)

An Exosomal miRNA Biomarker for the Detection of Pancreatic Ductal Adenocarcinoma
Dahkki: Amy Makler, et al.
Almmustuhtton: (2022-10-01)

Research progress of long non-coding RNA and miRNA in pathogenesis of preeclamp-sia
Dahkki: Ying LI, et al.
Almmustuhtton: (2023-08-01)

RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate
Dahkki: Cnop, M, et al.
Almmustuhtton: (2012)

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus
Dahkki: Travers, M, et al.
Almmustuhtton: (2010)

Discovering the ‘Dark matters’ in expression data of miRNA based on the miRNA-mRNA and miRNA-lncRNA networks
Dahkki: Cong Pian, et al.
Almmustuhtton: (2018-10-01)

MiRNA biogenesis. Part 1. Maturation of pre-miRNA. Maturation of canonical miRNAs
Dahkki: A.E. Abaturov, et al.
Almmustuhtton: (2021-04-01)

Plasma Level of miRNA-7, miRNA-409 and miRNA-93 as Potential Biomarkers for Colorectal Cancer
Dahkki: Maryam Zare, et al.
Almmustuhtton: (2019-01-01)

miRNA Signatures in Bronchopulmonary Dysplasia: Implications for Biomarkers, Pathogenesis, and Therapeutic Options
Dahkki: Hajime Maeda, et al.
Almmustuhtton: (2024-07-01)