The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis

Recent advances in the understanding of the genetics of type 2 diabetes (T2D) susceptibility have focused attention on the regulation of transcriptional activity within the pancreatic beta-cell. MicroRNAs (miRNAs) represent an important component of regulatory control, and have proven roles in the d...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Van De Bunt, M, Gaulton, K, Parts, L, Moran, I, Johnson, P, Lindgren, C, Ferrer, J, Gloyn, A, McCarthy, M
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Public Library of Science 2013

Những quyển sách tương tự

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.
Bằng: Martijn van de Bunt, et al.
Được phát hành: (2013-01-01)

Insights into β-cell biology and type 2 diabetes pathogenesis from studies of the islet transcriptome
Bằng: Van De Bunt, M, et al.
Được phát hành: (2014)

Human pancreatic islet miRNA-mRNA networks of altered miRNAs due to glycemic status
Bằng: Alexandros Karagiannopoulos, et al.
Được phát hành: (2022-04-01)

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Bằng: Thurner, M, et al.
Được phát hành: (2018)

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development.
Bằng: Wigard P Kloosterman, et al.
Được phát hành: (2007-08-01)

Computational and Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy
Bằng: Nalini Venkatesan, et al.
Được phát hành: (2015-01-01)

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.
Bằng: Pasquali, L, et al.
Được phát hành: (2014)

Computational and in vitro Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy
Bằng: Nalini Venkatesan, et al.
Được phát hành: (2015-05-01)

Expression of Concern: Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development.
Bằng: PLOS Biology Editors
Được phát hành: (2022-04-01)

The role of lncRNA and miRNA in the pathogenesis of renal fibrosis
Bằng: Liang CHANG, et al.
Được phát hành: (2023-04-01)

The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Bằng: Łukasz Pulik, et al.
Được phát hành: (2022-12-01)

Genetic regulation of RNA splicing in human pancreatic islets
Bằng: Goutham Atla, et al.
Được phát hành: (2022-09-01)

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
Bằng: Pasquali, L, et al.
Được phát hành: (2014)

miRNA-Mediated Immune Regulation in Islet Autoimmunity and Type 1 Diabetes
Bằng: Martin G. Scherm, et al.
Được phát hành: (2020-11-01)

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Bằng: Matthias Thurner, et al.
Được phát hành: (2018-02-01)

miRNA expression profile in rats correlates with type-2-diabetes phenotype
Bằng: Herrera, B, et al.
Được phát hành: (2008)

Gene expression analysis demonstrates presence of a non-coding RNA (ANRIL) in human islets and FACs sorted beta cells which has a potential regulatory role on CDKN2B expression
Bằng: Pal, A, et al.
Được phát hành: (2009)

ZIKV Infection and miRNA Network in Pathogenesis and Immune Response
Bằng: Carolina Manganeli Polonio, et al.
Được phát hành: (2021-10-01)

Mechanisms of genome regulation in human islets and their role in the pathogenesis of type 2 diabetes
Bằng: van de Bunt, G, et al.
Được phát hành: (2014)

MiR-184 expression is regulated by AMPK in pancreatic islets
Bằng: Martinez-Sanchez, A, et al.
Được phát hành: (2017)

CircRNA-miRNA-VEGFA: an important pathway to regulate cancer pathogenesis
Bằng: Lei Zhang, et al.
Được phát hành: (2023-05-01)

Clinical and biological significance of circulating miRNAs in chronic pancreatitis patients undergoing total pancreatectomy with islet autotransplantation
Bằng: Srividya Vasu, et al.
Được phát hành: (2023-10-01)

Differences between global miRNA expression profiles in diabetic and normoglycaemic rats
Bằng: Herrera, B, et al.
Được phát hành: (2008)

Major miRNA Involved in Insulin Secretion and Production in Beta-Cells
Bằng: Aghaei M, et al.
Được phát hành: (2020-03-01)

The miRNA pathway in neurological and skeletal muscle disease: implications for pathogenesis and therapy.
Bằng: Sibley, C, et al.
Được phát hành: (2011)

The miRNA pathway in neurological and skeletal muscle disease: Implications for pathogenesis and therapy
Bằng: Sibley, C, et al.
Được phát hành: (2011)

Regulation of miRNA content. Part 1. Editing miRNA. Тailing miRNA
Bằng: A.E. Abaturov, et al.
Được phát hành: (2021-06-01)

Real-time monitoring of miRNA function in pancreatic cell lines using recombinant AAV-based miRNA Asensors.
Bằng: Jing Chen, et al.
Được phát hành: (2013-01-01)

An Exosomal miRNA Biomarker for the Detection of Pancreatic Ductal Adenocarcinoma
Bằng: Amy Makler, et al.
Được phát hành: (2022-10-01)

Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model
Bằng: van de Bunt, M, et al.
Được phát hành: (2016)

Research progress of long non-coding RNA and miRNA in pathogenesis of preeclamp-sia
Bằng: Ying LI, et al.
Được phát hành: (2023-08-01)

RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate
Bằng: Cnop, M, et al.
Được phát hành: (2012)

Discovering the ‘Dark matters’ in expression data of miRNA based on the miRNA-mRNA and miRNA-lncRNA networks
Bằng: Cong Pian, et al.
Được phát hành: (2018-10-01)

MiRNA biogenesis. Part 1. Maturation of pre-miRNA. Maturation of canonical miRNAs
Bằng: A.E. Abaturov, et al.
Được phát hành: (2021-04-01)

Plasma Level of miRNA-7, miRNA-409 and miRNA-93 as Potential Biomarkers for Colorectal Cancer
Bằng: Maryam Zare, et al.
Được phát hành: (2019-01-01)

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus
Bằng: Travers, M, et al.
Được phát hành: (2010)

miRNA Signatures in Bronchopulmonary Dysplasia: Implications for Biomarkers, Pathogenesis, and Therapeutic Options
Bằng: Hajime Maeda, et al.
Được phát hành: (2024-07-01)

miRNA expression and interaction with the 3′UTR of FMR1 in FRAXopathy pathogenesis
Bằng: Alexander A. Dolskiy, et al.
Được phát hành: (2021-03-01)

Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies
Bằng: Abdul Q. Khan, et al.
Được phát hành: (2019-08-01)

Immunoregulatory framework and the role of miRNA in the pathogenesis of NSCLC – A systematic review
Bằng: Nikhil Samarth, et al.
Được phát hành: (2022-12-01)