Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials
The surface coverage and subsequent arginine-glycine-aspartic acid (RGD) derivatization of the Ti-6Al-4V surface which can be readily effected by silanization in amounts far higher on a surface-bound Ti phosphate interface that can be accomplished on the native oxide by standard methods were shown....
| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Journal article |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
2003
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| _version_ | 1826306381163003904 |
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| author | Gawalt, E Avaltroni, M Danahy, M Silverman, B Hanson, E Midwood, K Schwarzbauer, J Schwartz, J |
| author_facet | Gawalt, E Avaltroni, M Danahy, M Silverman, B Hanson, E Midwood, K Schwarzbauer, J Schwartz, J |
| author_sort | Gawalt, E |
| collection | OXFORD |
| description | The surface coverage and subsequent arginine-glycine-aspartic acid (RGD) derivatization of the Ti-6Al-4V surface which can be readily effected by silanization in amounts far higher on a surface-bound Ti phosphate interface that can be accomplished on the native oxide by standard methods were shown. Nonetheless, the inherent hydrolytic instability under physiological conditions of surface siloxanes ultimately limits their utility. Thus, a successful surface chemistry approach for creating stable osteoconductive surfaces on Ti and Ti-6Al-4V was found. |
| first_indexed | 2024-03-07T06:47:06Z |
| format | Journal article |
| id | oxford-uuid:fb3a67c5-b26f-4b37-9ef7-1d0a764ef382 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:47:06Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:fb3a67c5-b26f-4b37-9ef7-1d0a764ef3822022-03-27T13:12:11ZBonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materialsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fb3a67c5-b26f-4b37-9ef7-1d0a764ef382EnglishSymplectic Elements at Oxford2003Gawalt, EAvaltroni, MDanahy, MSilverman, BHanson, EMidwood, KSchwarzbauer, JSchwartz, JThe surface coverage and subsequent arginine-glycine-aspartic acid (RGD) derivatization of the Ti-6Al-4V surface which can be readily effected by silanization in amounts far higher on a surface-bound Ti phosphate interface that can be accomplished on the native oxide by standard methods were shown. Nonetheless, the inherent hydrolytic instability under physiological conditions of surface siloxanes ultimately limits their utility. Thus, a successful surface chemistry approach for creating stable osteoconductive surfaces on Ti and Ti-6Al-4V was found. |
| spellingShingle | Gawalt, E Avaltroni, M Danahy, M Silverman, B Hanson, E Midwood, K Schwarzbauer, J Schwartz, J Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials |
| title | Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials |
| title_full | Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials |
| title_fullStr | Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials |
| title_full_unstemmed | Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials |
| title_short | Bonding organics to Ti alloys: Facilitating human osteoblast attachment and spreading on surgical implant materials |
| title_sort | bonding organics to ti alloys facilitating human osteoblast attachment and spreading on surgical implant materials |
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