Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

Εμφάνιση άλλων εκδόσεων (1)

Ferrous ion and 2-oxoglutarate (2OG) oxygenases catalyze the demethylation of N(epsilon)-methylated lysine residues in histones. Here we report studies on the inhibition of the JMJD2 subfamily of histone demethylases, employing binding analyses by nondenaturing mass spectrometry (MS), dynamic combin...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Rose, N, Woon, E, Kingham, G, King, O, Mecinović, J, Clifton, I, Ng, S, Talib-Hardy, J, Oppermann, U, McDonough, M, Schofield, C
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2010
Θέματα:	Binding, Competitive Spectrometry, Mass, Electrospray Ionization Binding Sites analogs and derivatives chemistry Tyrosine Structure-Activity Relationship Crystallography, X-Ray chemical synthesis Models, Molecular Combinatorial Chemistry Techniques Oxalic Acids antagonists and inhibitors Jumonji Domain-Containing Histone Demethylases Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Παρόμοια τεκμήρια

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species
ανά: Stephen B. Milne, κ.ά.
Έκδοση: (2005-08-01)

Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.
ανά: Rose, N, κ.ά.
Έκδοση: (2010)

Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples
ανά: Xianlin Han, κ.ά.
Έκδοση: (2006-04-01)

Extractive electrospray ionization mass spectrometry for analytical evaluation and synthetic preparation of pharmaceutical chemicals
ανά: Manman Qin, κ.ά.
Έκδοση: (2023-01-01)

Investigating the regulation of membrane protein assemblies by lipids and other small molecules using native mass spectrometry
ανά: Shutin, D
Έκδοση: (2020)

Protein phosphorylation analysis by electrospray mass spectrometry : a guide to concepts and practice /
ανά: 507924 Lehmann, Wolf D.
Έκδοση: (2011)

Chemical reactivity hazard training [electronic resource] /
Έκδοση: (2006)

Espectrometria de massas com ionização por "electrospray": processos químicos envolvidos na formação de íons de substâncias orgânicas de baixo peso molecular
ανά: Crotti Antônio Eduardo Miller, κ.ά.
Έκδοση: (2006-01-01)

Study on the Structural Effect of Maltoligosaccharides on Cytochrome c Complexes Stabilities by Native Mass Spectrometry
ανά: Quan Chi, κ.ά.
Έκδοση: (2018-01-01)

Comparison of Plasma Ionization- and Secondary Electrospray Ionization- High-resolution Mass Spectrometry for Real-time Breath Analysis
ανά: Jiafa Zeng, κ.ά.
Έκδοση: (2022-02-01)

Seminolipid and its precursor/degradative product, galactosylalkylacylglycerol, in the testis of saposin A- and prosaposin-deficient mice
ανά: Keiko Tadano-Aritomi, κ.ά.
Έκδοση: (2003-09-01)

A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A
ανά: Andrew J. Norris, κ.ά.
Έκδοση: (2005-10-01)

Characterization of Nucleosides and Nucleobases in Natural Cordyceps by HILIC–ESI/TOF/MS and HILIC–ESI/MS
ανά: Bin Yang, κ.ά.
Έκδοση: (2013-08-01)

Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry
ανά: Megan A Rounds, κ.ά.
Έκδοση: (2012-07-01)

Estudo por espectrometria de massas de soluções de hidróxi(tosilóxi)iodobenzeno: propostas para mecanismos de desproporção
ανά: Ramon S. Vasconcelos, κ.ά.
Έκδοση: (2012-01-01)

Identification of phosphatidylserylglutamate: a novel minor lipid in Escherichia coli
ανά: Teresa A. Garrett, κ.ά.
Έκδοση: (2009-08-01)

Copper complexes formed by 3,5-bis(2,2′-bipyridin-4-ylethynyl)benzoic acid and its methyl and ethyl esters as studied by electrospray ionization mass spectrometry
ανά: Frański Rafał, κ.ά.
Έκδοση: (2013-12-01)

Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS)
ανά: G. Liebisch, κ.ά.
Έκδοση: (1999-08-01)

ESI-MS spectra of 3-cyano-4-(substituted phenyl)-6-phenyl-2(1H)-pyridinones
ανά: BRATISLAV Ž. JOVANOVIĆ, κ.ά.
Έκδοση: (2009-03-01)

Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells
ανά: Anthony D. Postle, κ.ά.
Έκδοση: (2006-06-01)

A miniaturized screen for inhibitors of Jumonji histone demethylases.
ανά: Sakurai, M, κ.ά.
Έκδοση: (2010)

Electrospray ionization mass spectrometric study of mercury complexes of N-heterocyclic carbenes derived from 1,2,4-triazolium salt precursors
ανά: Frański Rafał, κ.ά.
Έκδοση: (2007-03-01)

DMS as an orthogonal separation to LC/ESI/MS/MS for quantifying isomeric cerebrosides in plasma and cerebrospinal fluid[S]
ανά: Hongbin Xu, κ.ά.
Έκδοση: (2019-01-01)

Structural Characterization of Flavonoid Glycoconjugates and Their Derivatives with Mass Spectrometric Techniques
ανά: Piotr Kachlicki, κ.ά.
Έκδοση: (2016-11-01)

Identification of Endocrine-Disrupting Compounds Using Nanoelectrospray Ionization Mass Spectrometry
ανά: Cédric Bovet, κ.ά.
Έκδοση: (2008-05-01)

Moderate Signal Enhancement in Electrospray Ionization Mass Spectrometry by Focusing Electrospray Plume with a Dielectric Layer around the Mass Spectrometer’s Orifice
ανά: Zi Qing Chua, κ.ά.
Έκδοση: (2024-01-01)

Preparing Apigenin from Leaves of Adinandra nitida
ανά: Zhengxiang Ning, κ.ά.
Έκδοση: (2008-01-01)

Comment on Villalva et al. Antioxidant, Anti-Inflammatory, and Antibacterial Properties of an <i>Achillea millefolium</i> L. Extract and Its Fractions Obtained by Supercritical Anti-Solvent Fractionation against <i>Helicobacter pylori</i>. <i>Antioxidants</i> 2022, <i>11</i>, 1849
ανά: Rafał Frański, κ.ά.
Έκδοση: (2023-06-01)

Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections
ανά: Margaux Fresnais, κ.ά.
Έκδοση: (2022-06-01)

Accurate Quantification of Lipid Species by Electrospray Ionization Mass Spectrometry — Meets a Key Challenge in Lipidomics
ανά: Kui Yang, κ.ά.
Έκδοση: (2011-11-01)

Recent advancements in nanoelectrospray ionization interface and coupled devices
ανά: Shiyi Chen, κ.ά.
Έκδοση: (2022-11-01)

Fabricating an Electrospray Ionization Chip Based on Induced Polarization and Liquid Splitting
ανά: Lvhan Zhou, κ.ά.
Έκδοση: (2021-08-01)

Chromium interaction with O-donor humic-like ligands using electrospray-ionization mass spectrometry
ανά: Anđelković Darko H., κ.ά.
Έκδοση: (2013-01-01)

Overcharging Effect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates
ανά: Lilla Pethő, κ.ά.
Έκδοση: (2019-08-01)

Toward Depth-Resolved Analysis of Plant Metabolites by Nanospray Desorption Electrospray Ionization Mass Spectrometry
ανά: Sangwon Cha, κ.ά.
Έκδοση: (2022-11-01)

Examining Interactions of Uranyl(VI) Ions with Amino Acids in the Gas Phase
ανά: Ana F. Lucena, κ.ά.
Έκδοση: (2023-03-01)

Detecting Intermediates and Products of Fast Heterogeneous Reactions on Liquid Surfaces via Online Mass Spectrometry
ανά: Agustín J. Colussi, κ.ά.
Έκδοση: (2019-01-01)

Electrospray mass spectrometry of human hair wax esters
ανά: Fitzgerald Mark, κ.ά.
Έκδοση: (2007-05-01)

Shotgun lipidomics of phosphoethanolamine-containing lipids in biological samples after one-step in situ derivatization
ανά: Xianlin Han, κ.ά.
Έκδοση: (2005-07-01)

Ambient ionization mass spectrometry /
ανά: Cody, Robert, κ.ά.
Έκδοση: (2015)