Pharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infants.

Pharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infants.

BACKGROUND: Although dihydroartemisinin-piperaquine (DP) is used primarily in children, pharmacokinetic/pharmacodynamic (PK/PD) data on DP use in young children are lacking. METHODS: We conducted a prospective PK/PD study of piperaquine in 107 young children in Uganda. Samples were collected up to 2...

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Detalles Bibliográficos
Main Authors: Creek, D, Bigira, V, McCormack, S, Arinaitwe, E, Wanzira, H, Kakuru, A, Tappero, J, Sandison, T, Lindegardh, N, Nosten, F, Aweeka, F, Parikh, S
Formato: Journal article
Idioma:English
Publicado: 2013

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