Neurofilament heavy chain in CSF correlates with relapses and disability in multiple sclerosis.

OBJECTIVE: Neurodegeneration is now accepted as a pathologic hallmark of multiple sclerosis (MS). We sought to discover whether CSF levels of neurofilament heavy chain protein (NfH(SMI35)) correlate with disability, disease activity, or specific stages of MS. METHODS: An electrochemiluminescence im...

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Bibliografiske detaljer
Main Authors: Kuhle, J, Leppert, D, Petzold, A, Regeniter, A, Schindler, C, Mehling, M, Anthony, D, Kappos, L, Lindberg, R
Format: Journal article
Sprog:English
Udgivet: 2011