Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.

Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.

The CD44 cell surface glycoprotein is expressed on a broad range of different tissues as multiple isoforms containing from one to ten alternatively spliced exons v1-v10 inserted within the extracellular domain. Differential glycosylation generates still further variability, yielding both N- and O-gl...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Jackson, D, Bell, J, Dickinson, R, Timans, J, Shields, J, Whittle, N
Materialtyp:	Journal article
Språk:	English
Publicerad:	1995

Liknande verk

Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.
av: Screaton, G, et al.
Publicerad: (1992)

Regulation of growth and dissemination of a human lymphoma by CD44 splice variants.
av: Bartolazzi, A, et al.
Publicerad: (1995)

Inducible expression of CD44 heparan sulphate proteoglycan splice variants on human monocytes during inflammation.
av: Jackson, D, et al.
Publicerad: (1996)

Specificity of 6th Workshop CD44 panel antibodies for alternatively spliced exons and their effects on lymphocyte activation and hyaluronan binding.
av: Bannerji, S, et al.
Publicerad: (1996)

THE STRUCTURE OF THE GENE ENCODING THE ALTERNATIVELY SPLICED CD44 GLYCOPROTEIN
av: Jackson, D, et al.
Publicerad: (1993)

Universal alternative splicing of noncoding exons
av: Deveson, I, et al.
Publicerad: (2018)

Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons.
av: Bennett, K, et al.
Publicerad: (1995)

Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain.
av: Jackson, D, et al.
Publicerad: (1992)

The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat.
av: Screaton, G, et al.
Publicerad: (1993)

CD44 isoform expression mediated by alternative splicing: tissue-specific regulation in mice.
av: Hirano, H, et al.
Publicerad: (1994)

Tissue-specific classification of alternatively spliced human exons
av: Rothman, Craig Jeremy
Publicerad: (2008)

Studies of exon scrambling and mutually exclusive alternative splicing
av: Kong, Rong, 1979-
Publicerad: (2005)

Expression of alternatively spliced forms of the CD44 extracellular-matrix receptor on human lung carcinomas.
av: Jackson, D, et al.
Publicerad: (1994)

Characterization of regulatory mechanisms for BIM exon 3 alternative splicing
av: Bhadra, Malini
Publicerad: (2017)

A putative exonic splicing enhancer in exon 7 of the PDHA1 gene affects splicing of adjacent exons.
av: Ridout, C, et al.
Publicerad: (2008)

CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion
av: Yin, Hao, et al.
Publicerad: (2019)

CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor.
av: Bennett, K, et al.
Publicerad: (1995)

TBX3 and its splice variant TBX3 + exon 2a are functionally similar.
av: Hoogaars, WM, et al.
Publicerad: (2008)

Characterization of trans-acting splicing factors that regulate BIM exon 3 splicing
av: Loh, Yan Ping
Publicerad: (2016)

The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.
av: Thornton, J, et al.
Publicerad: (2006)

The evolution of novelty in conserved genes; evidence of positive selection in the Drosophila fruitless gene is localised to alternatively spliced exons
av: Parker, D, et al.
Publicerad: (2013)

The evolution of novelty in conserved genes; evidence of positive selection in the Drosophila fruitless gene is localised to alternatively spliced exons.
av: Parker, D, et al.
Publicerad: (2014)

A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.
av: Zilch, C, et al.
Publicerad: (1998)

CD44 and cancer.
av: Jackson, D, et al.
Publicerad: (1993)

Glycoproterin and proteoglycan techniques/
av: 187076 Beeley, J. G.
Publicerad: (1985)

Proteoglycan protocols /
av: Iozzo, Renato V.
Publicerad: (2001)

Activation of an exonic splice-donor site in exon 30 of CDK5RAP2 in a patient with severe microcephaly and pigmentary abnormalities
av: Pagnamenta, A, et al.
Publicerad: (2016)

Exon array analysis of head and neck cancers identifies a hypoxia related splice variant of LAMA3 associated with a poor prognosis
av: Moller-Levet, C, et al.
Publicerad: (2009)

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
av: Sathasivam, Kirupa, et al.
Publicerad: (2013)

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
av: Sathasivam, Kirupa, et al.
Publicerad: (2013)

Alternative splicing in the postgenomic era /
av: Blencowe, Benjamin J., et al.
Publicerad: (2007)

A novel alternatively spliced variant of the human macrophage scavenger receptor gene
av: Gough, P, et al.
Publicerad: (1996)

Alternative splicing and disease /
av: Jeanteur, Ph. (Philippe)
Publicerad: (2006)

Partial rescue of truncating mutations in the ATRX gene through unusual intra-exonic splicing
av: Malik, N, et al.
Publicerad: (2006)

Human leucocyte heparan sulphate proteoglycans and their roles in inflammation.
av: Jackson, D
Publicerad: (1997)

Cross-kingdom patterns of alternative splicing and splice recognition
av: McGuire, Abigail Manson, et al.
Publicerad: (2010)

THE GENOMIC ORGANIZATION OF THE HUMAN CD44 GENE
av: Bell, M, et al.
Publicerad: (1993)

Heparan sulfate proteoglycan isoforms of the CD44 hyaluronan receptor induced in human inflammatory macrophages can function as paracrine regulators of fibroblast growth factor action.
av: Jones, M, et al.
Publicerad: (2000)

LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing.
av: Screaton, G, et al.
Publicerad: (1997)

Alternative splicing and the evolution of phenotypic novelty.
av: Bush, S, et al.
Publicerad: (2016)