High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency

Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited human enzyme defect. This deficiency provides some protection from clinical malaria, but it can also cause haemolysis after administration of drugs with oxidant properties. Methods The safety of chlorproguani...

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Main Authors: Fanello, C, Karema, C, Avellino, P, Bancone, G, Uwimana, A, Lee, S, D'Alessandro, U, Modiano, D
格式: Journal article
语言:English
出版: Public Library of Science 2008