Mitochondrial fragmentation in neuronal degeneration: Toward an understanding of HD striatal susceptibility
Huntington's disease (HD) is an autosomal-dominant progressive neurodegenerative disorder that primarily affects medium spiny neurons within the striatum. HD is caused by inheritance of an expanded CAG repeat in the HTT gene, resulting in a mutant huntingtin (mHtt) protein containing extra glut...
| المؤلفون الرئيسيون: | , |
|---|---|
| التنسيق: | Journal article |
| منشور في: |
Elsevier
2016
|