Mitochondrial fragmentation in neuronal degeneration: Toward an understanding of HD striatal susceptibility

Mitochondrial fragmentation in neuronal degeneration: Toward an understanding of HD striatal susceptibility

Huntington's disease (HD) is an autosomal-dominant progressive neurodegenerative disorder that primarily affects medium spiny neurons within the striatum. HD is caused by inheritance of an expanded CAG repeat in the HTT gene, resulting in a mutant huntingtin (mHtt) protein containing extra glut...

Полное описание

Библиографические подробности
Главные авторы:	Cherubini, M, Ginés, S
Формат:	Journal article
Опубликовано:	Elsevier 2016

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