Mitochondrial fragmentation in neuronal degeneration: Toward an understanding of HD striatal susceptibility
Huntington's disease (HD) is an autosomal-dominant progressive neurodegenerative disorder that primarily affects medium spiny neurons within the striatum. HD is caused by inheritance of an expanded CAG repeat in the HTT gene, resulting in a mutant huntingtin (mHtt) protein containing extra glut...
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| Materyal Türü: | Journal article |
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Elsevier
2016
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