Assessing white matter ischemic damage in dementia patients by measurement of myelin proteins.

White matter ischemia is difficult to quantify histologically. Myelin-associated glycoprotein (MAG) is highly susceptible to ischemia, being expressed only adaxonally, far from the oligodendrocyte cell body. Myelin-basic protein (MBP) and proteolipid protein (PLP) are expressed throughout the myelin...

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Detalhes bibliográficos
Main Authors: Barker, R, Wellington, D, Esiri, M, Love, S
Formato: Journal article
Idioma:English
Publicado em: 2013