PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
Peroxisome proliferator activated receptor gamma 2 (PPARg2) is the nutritionally regulated isoform of PPARg. Ablation of PPARg2 in the ob/ob background, PPARg2<sup>-/-</sup> Lep<sup>ob</sup>/Lep<sup>ob</sup> (POKO mouse), resulted in decreased fat mass, severe ins...
Glavni autori: | Medina-Gomez, G, Gray, S, Yetukuri, L, Shimomura, K, Virtue, S, Campbell, M, Curtis, R, Jimenez-Linan, M, Blount, M, Yeo, G, Lopez, M, Seppanen-Laakso, T, Ashcroft, F, Oresic, M, Vidal-Puig, A |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
Public Library of Science
2007
|
Slični predmeti
-
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
od: Gema Medina-Gomez, i dr.
Izdano: (2007-04-01) -
Cardio-Lipotoxicity of Epicardial Adipose Tissue
od: Monica L. Bodenstab, i dr.
Izdano: (2024-11-01) -
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.
od: Medina-Gomez, G, i dr.
Izdano: (2005) -
DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle[S]
od: Li Liu, i dr.
Izdano: (2011-04-01) -
Enhanced oleate uptake and lipotoxicity associated with laurate
od: Yasuyuki Kitaura, i dr.
Izdano: (2015-01-01)