Addressable high-information-density DNA nanostructures

Addressable high-information-density DNA nanostructures

We present a strategy for self-assembly of the smallest yet reported DNA nanostructures that are also addressable in terms of their DNA-base code. Using linear as well as novel branched three-way DNA oligonucleotide building-blocks we demonstrate the formation of a nano-network's fundamental ce...

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Bibliographic Details
Main Authors: Tumpane, J, Sandin, P, Kumar, R, Powers, V, Lundberg, E, Gale, N, Baglioni, P, Lehn, J, Albinsson, B, Lincoln, P, Wilhelmsson, L, Brown, T, Norden, B
Format: Journal article
Language:English
Published: 2007
Description
Summary:We present a strategy for self-assembly of the smallest yet reported DNA nanostructures that are also addressable in terms of their DNA-base code. Using linear as well as novel branched three-way DNA oligonucleotide building-blocks we demonstrate the formation of a nano-network's fundamental cell, a DNA pseudo-hexagon of side 4 nm. The network's inherent addressability will allow functionalization with sub-nanometer precision yielding unprecedented richness in information density, important in the context of Moore's Law and nano-chip technology. © 2007.

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