Synergistic activity of letrozole and sorafenib on breast cancer cells.

Synergistic activity of letrozole and sorafenib on breast cancer cells.

Estrogens induce breast tumor cell proliferation by directly regulating gene expression via the estrogen receptor (ER) transcriptional activity and by affecting growth factor signaling pathways such as mitogen-activated protein kinase (MAPK) and AKT/mammalian target of rapamycin Complex1 (mTORC1) ca...

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Bibliographic Details
Main Authors:	Bonelli, M, Fumarola, C, Alfieri, R, La Monica, S, Cavazzoni, A, Galetti, M, Gatti, R, Belletti, S, Harris, A, Fox, S, Evans, D, Dowsett, M, Martin, L, Bottini, A, Generali, D, Petronini, P
Format:	Journal article
Language:	English
Published:	2010

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