SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE
The only protection required in a five-step synthesis of the α-L-fucosidase inhibitor, deoxyfuconojirimycin [1,5-dideoxy-1,5-imino-L- fucitol] from D-lyxonolactone, a readily available chiral pool material, is a single isopropylidene group.
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1989
|
| _version_ | 1826306497854832640 |
|---|---|
| author | Fleet, G Petursson, S Campbell, A Mueller, R Behling, J Babiak, K Ng, J Scaros, M |
| author_facet | Fleet, G Petursson, S Campbell, A Mueller, R Behling, J Babiak, K Ng, J Scaros, M |
| author_sort | Fleet, G |
| collection | OXFORD |
| description | The only protection required in a five-step synthesis of the α-L-fucosidase inhibitor, deoxyfuconojirimycin [1,5-dideoxy-1,5-imino-L- fucitol] from D-lyxonolactone, a readily available chiral pool material, is a single isopropylidene group. |
| first_indexed | 2024-03-07T06:48:51Z |
| format | Journal article |
| id | oxford-uuid:fbced0f6-b30f-4e46-b3c6-ace8a423c9cb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:48:51Z |
| publishDate | 1989 |
| record_format | dspace |
| spelling | oxford-uuid:fbced0f6-b30f-4e46-b3c6-ace8a423c9cb2022-03-27T13:16:29ZSHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONEJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fbced0f6-b30f-4e46-b3c6-ace8a423c9cbEnglishSymplectic Elements at Oxford1989Fleet, GPetursson, SCampbell, AMueller, RBehling, JBabiak, KNg, JScaros, MThe only protection required in a five-step synthesis of the α-L-fucosidase inhibitor, deoxyfuconojirimycin [1,5-dideoxy-1,5-imino-L- fucitol] from D-lyxonolactone, a readily available chiral pool material, is a single isopropylidene group. |
| spellingShingle | Fleet, G Petursson, S Campbell, A Mueller, R Behling, J Babiak, K Ng, J Scaros, M SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE |
| title | SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE |
| title_full | SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE |
| title_fullStr | SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE |
| title_full_unstemmed | SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE |
| title_short | SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE |
| title_sort | short efficient synthesis of the alpha l fucosidase inhibitor deoxyfuconojirimycin 1 5 dideoxy 1 5 imino l fucitol from d lyxonolactone |
| work_keys_str_mv | AT fleetg shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT peturssons shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT campbella shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT muellerr shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT behlingj shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT babiakk shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT ngj shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone AT scarosm shortefficientsynthesisofthealphalfucosidaseinhibitordeoxyfuconojirimycin15dideoxy15iminolfucitolfromdlyxonolactone |