Structural basis for the acceleration of procollagen processing by Procollagen C-Proteinase Enhancer-1

Structural basis for the acceleration of procollagen processing by Procollagen C-Proteinase Enhancer-1

Procollagen C-proteinase enhancer-1 (PCPE-1) is a secreted protein that specifically accelerates proteolytic release of the C-propeptides from fibrillar procollagens, a crucial step in fibril assembly. As such, it is a potential therapeutic target to improve tissue repair and prevent fibrosis, a maj...

Bibliografski detalji
Glavni autori:	Pulido, D, Sharma, U, Goff, S, Hussain, S-A, Cordes, S, Mariano, N, Bettler, E, Moali, C, Aghajari, N, Hohenester, E, Hulmes, DJS
Format:	Journal article
Jezik:	English
Izdano:	Elsevier 2018

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