A genome-wide screen for susceptibility loci in ankylosing spondylitis.
OBJECTIVE: To localize the regions containing genes that determine susceptibility to ankylosing spondylitis (AS). METHODS: One hundred five white British families with 121 affected sibling pairs with AS were recruited, largely from the Royal National Hospital for Rheumatic Diseases AS database. A g...
Main Authors: | Brown, M, Pile, K, Kennedy, L, Campbell, D, Andrew, L, March, R, Shatford, J, Weeks, D, Calin, A, Wordsworth, B |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1998
|
Similar Items
-
The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998) -
Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci.
by: Laval, S, et al.
Published: (2001) -
The role of germline polymorphisms in the T-cell receptor in susceptibility to ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998) -
Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis.
by: Brown, M, et al.
Published: (1998) -
Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment.
by: Brown, M, et al.
Published: (1997)