The influence of molecular reach and diffusivity on the efficacy of membrane-confined reactions
Signaling by surface receptors often relies on tethered reactions whereby an enzyme bound to the cytoplasmic tail of a receptor catalyzes reactions on substrates within reach. The overall length and stiffness of the receptor tail, the enzyme, and the substrate determine a biophysical parameter terme...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
Cell Press
2019
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