Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
<p>Endoplasmic reticulum (ER)-associated degradation (ERAD) of misfolded proteins of the secretory pathway is crucial for ER homeostasis and the physiological importance of this mechanism is reflected by more than 60 diseases that have been linked to ERAD to date. The best characterised mammal...
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| Format: | Thesis |
| Language: | English |
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2013
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