Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

Glucocorticoids (GCs), which are used in the treatment of immune-mediated inflammatory diseases, inhibit the expression of many inflammatory mediators. They can also induce the expression of dual specificity phosphatase 1 (DUSP1; otherwise known as mitogen-activated protein kinase [MAPK] phosphatase...

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Detalhes bibliográficos
Principais autores: Abraham, S, Lawrence, T, Kleiman, A, Warden, P, Medghalchi, M, Tuckermann, J, Saklatvala, J, Clark, A
Formato: Journal article
Idioma:English
Publicado em: 2006