Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

Ongoing treatments for genetic developmental disorders of the central nervous system are mostly symptomatic and do not correct the genetic cause. Recent identification of common mechanisms between diseases has suggested that new therapeutic targets could be applied across intellectual disabilities w...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Faundez, V, De Toma, I, Bardoni, B, Bartesaghi, R, Nizetic, D, de la Torre, R, Kadosh, R, Herault, Y, Dierssen, M, Potier, M-C
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Elsevier 2018

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-н: Małgorzata Drozd, зэрэг
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-н: Alessandra Tempio, зэрэг
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-н: Tovi Anderson, зэрэг
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-н: Sara Castagnola, зэрэг
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Síndrome frágil X Fragile X syndrome
-н: Miguel Lugones Botell, зэрэг
Хэвлэсэн: (2006-09-01)

The fragile X syndrome.
-н: Flannery, A, зэрэг
Хэвлэсэн: (1995)

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions
-н: Snow Bach, зэрэг
Хэвлэсэн: (2021-11-01)

CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome
-н: Barbara eBardoni, зэрэг
Хэвлэсэн: (2014-03-01)

The fragile X syndrome.
-н: Hirst, M, зэрэг
Хэвлэсэн: (1992)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID and Fragile X syndrome
-н: Siew, Wei Hong, зэрэг
Хэвлэсэн: (2013)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID and Fragile X syndrome
-н: Wei-Hong eSiew, зэрэг
Хэвлэсэн: (2013-04-01)

Síndrome frágil X Fragile X Syndrome
Хэвлэсэн: (2007-03-01)

Learning Potential is Useful in Pre-schoolers with Fragile X and Down Syndrome
-н: Mª Auxiliadora Robles-Bello, зэрэг
Хэвлэсэн: (2018-04-01)

Molecular studies of the fragile X syndrome.
-н: Knight, S, зэрэг
Хэвлэсэн: (1992)

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19
-н: Ilario De Toma, зэрэг
Хэвлэсэн: (2021-01-01)

The impact of autism spectrum disorder symptoms on gesture use in fragile X syndrome and Down syndrome
-н: Emily Lorang, зэрэг
Хэвлэсэн: (2017-12-01)

Drugs development and fragile X syndrome translational success story
-н: Budimirović Dejan, зэрэг
Хэвлэсэн: (2016-01-01)

Fragile X Syndrome
-н: J Gordon Millichap
Хэвлэсэн: (1987-11-01)

Fragile-X Syndrome
-н: J Gordon Millichap
Хэвлэсэн: (1988-03-01)

Prenatal diagnosis of fragile X syndrome.
-н: Hirst, M, зэрэг
Хэвлэсэн: (1991)

Social Factors Influence Behavior in the Novel Object Recognition Task in a Mouse Model of Down Syndrome
-н: Cesar Sierra, зэрэг
Хэвлэсэн: (2021-11-01)

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome
-н: Jonathan W. Lovelace, зэрэг
Хэвлэсэн: (2018-07-01)

Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome
-н: Sang S. Seo, зэрэг
Хэвлэсэн: (2022-06-01)

Psychopathology in Fragile X Syndrome
-н: J Gordon Millichap
Хэвлэсэн: (1989-02-01)

Fragile X Syndrome Recognition
-н: J Gordon Millichap
Хэвлэсэн: (1989-02-01)

Neuroanatomy of Fragile X Syndrome
-н: J Gordon Millichap
Хэвлэсэн: (1991-02-01)

Diagnosis of Fragile X Syndrome
-н: J Gordon Millichap
Хэвлэсэн: (1991-12-01)

Epilepsy and Fragile X Syndrome
-н: J Gordon Millichap
Хэвлэсэн: (2003-01-01)

Fragile X Syndrome Workshop
-н: J Gordon Millichap
Хэвлэсэн: (2000-10-01)

Astrocytes in fragile X syndrome
-н: Karo Talvio, зэрэг
Хэвлэсэн: (2024-01-01)

Screening for fragile X syndrome.
-н: Murray, зэрэг
Хэвлэсэн: (1997-01-01)

Analysis of a Repetitive Language Coding System: Comparisons between Fragile X Syndrome, Autism, and Down Syndrome
-н: Anne Hoffmann, зэрэг
Хэвлэсэн: (2022-04-01)

Specificity: A Phenotypic Comparison of Communication-Relevant Domains Between Youth With Down Syndrome and Fragile X Syndrome
-н: Laura del Hoyo Soriano, зэрэг
Хэвлэсэн: (2018-10-01)

Molecular analysis of the fragile X syndrome.
-н: Knight, S, зэрэг
Хэвлэсэн: (1992)

Pathological Plasticity in Fragile X Syndrome
-н: Brandon S. Martin, зэрэг
Хэвлэсэн: (2012-01-01)

Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome
-н: Tomer Illouz, зэрэг
Хэвлэсэн: (2021-06-01)

Origins of the fragile X syndrome mutation.
-н: Hirst, M, зэрэг
Хэвлэсэн: (1993)

Genotype prediction in the fragile X syndrome.
-н: Hirst, M, зэрэг
Хэвлэсэн: (1991)

Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
-н: Rochelle L. Coulson, зэрэг
Хэвлэсэн: (2024-04-01)