The role of the exopolyphosphatase PPX in avoidance by Neisseria meningitidis of complement-mediated killing.

The complement system is critical for immunity against the important human pathogen Neisseria meningitidis. We describe the isolation of a meningococcal mutant lacking PPX, an exopolyphosphatase responsible for cleaving cellular polyphosphate, a polymer of tens to hundreds of orthophosphate residues...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Zhang, Q, Li, Y, Tang, C
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2010