The role of the exopolyphosphatase PPX in avoidance by Neisseria meningitidis of complement-mediated killing.

The complement system is critical for immunity against the important human pathogen Neisseria meningitidis. We describe the isolation of a meningococcal mutant lacking PPX, an exopolyphosphatase responsible for cleaving cellular polyphosphate, a polymer of tens to hundreds of orthophosphate residues...

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Bibliografiset tiedot
Päätekijät: Zhang, Q, Li, Y, Tang, C
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2010