The structure of phosphorylase kinase holoenzyme at 9.9 angstroms resolution and location of the catalytic subunit and the substrate glycogen phosphorylase.
Phosphorylase kinase (PhK) coordinates hormonal and neuronal signals to initiate the breakdown of glycogen. The enzyme catalyzes the phosphorylation of inactive glycogen phosphorylase b (GPb), resulting in the formation of active glycogen phosphorylase a. We present a 9.9 angstroms resolution struct...
Κύριοι συγγραφείς: | Vénien-Bryan, C, Jonic, S, Skamnaki, V, Brown, N, Bischler, N, Oikonomakos, N, Boisset, N, Johnson, L |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2009
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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ανά: Bichard, C, κ.ά.
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GLUCOSE ANALOG INHIBITORS OF GLYCOGEN-PHOSPHORYLASE
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Calcineurin B-like domains in the large regulatory alpha/beta subunits of phosphorylase kinase.
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