A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling.

A phosphine-free palladium catalyst for aqueous Suzuki-Miyaura cross-coupling is presented. The catalyst is active enough to mediate hindered, ortho-substituted biaryl couplings but mild enough for use on peptides and proteins. The Suzuki-Miyaura couplings on protein substrates are the first to proc...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Chalker, J, Wood, C, Davis, B
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2009

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