A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling.

A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling.

A phosphine-free palladium catalyst for aqueous Suzuki-Miyaura cross-coupling is presented. The catalyst is active enough to mediate hindered, ortho-substituted biaryl couplings but mild enough for use on peptides and proteins. The Suzuki-Miyaura couplings on protein substrates are the first to proc...

Полное описание

Библиографические подробности
Главные авторы:	Chalker, J, Wood, C, Davis, B
Формат:	Journal article
Язык:	English
Опубликовано:	2009

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