A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling.

A phosphine-free palladium catalyst for aqueous Suzuki-Miyaura cross-coupling is presented. The catalyst is active enough to mediate hindered, ortho-substituted biaryl couplings but mild enough for use on peptides and proteins. The Suzuki-Miyaura couplings on protein substrates are the first to proc...

全面介绍

书目详细资料
Main Authors: Chalker, J, Wood, C, Davis, B
格式: Journal article
语言:English
出版: 2009