Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa

Imaging techniques have revolutionised the assessment of retinal disease in humans and animal models. Here we describe a novel technique for the in vivo visualisation of rod photoreceptors which permits semiquantitative assessment of outer retinal degeneration, and validate this approach in two mous...

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Détails bibliographiques
Auteurs principaux: Orlans, HO, Barnard, AR, MacLaren, RE
Format: Journal article
Langue:English
Publié: Elsevier 2019