Block of ATP-sensitive K+ channels in isolated mouse pancreatic beta-cells by 2,3-butanedione monoxime.

Block of ATP-sensitive K+ channels in isolated mouse pancreatic beta-cells by 2,3-butanedione monoxime.

Show other versions (1)

1. The patch-clamp technique has been used to examine the action of the chemical phosphatase 2,3-butanedione monoxime (BDM) on ATP-sensitive K+ channels (KATP-channels) from mouse isolated pancreatic beta-cells in the absence of ATP and Mg2+. 2. BDM reversibly inhibited whole-cell KATP-currents with...

Full description

Bibliographic Details
Main Authors:	Smith, P, Williams, B, Ashcroft, F
Format:	Journal article
Language:	English
Published:	1994

Similar Items

BLOCK OF ATP-SENSITIVE K+ CHANNELS IN ISOLATED MOUSE PANCREATIC BETA-CELLS BY 2,3-BUTANEDIONE MONOXIME
by: Smith, P, et al.
Published: (1993)

RUNDOWN OF ATP-SENSITIVE K-CURRENTS IN MOUSE PANCREATIC BETA-CELLS
by: Williams, B, et al.
Published: (1992)

The Ba2+ block of the ATP-sensitive K+ current of mouse pancreatic beta-cells.
by: Takano, M, et al.
Published: (1996)

Effects of internal chloride on ATP-sensitive K-channels in mouse pancreatic beta-cells.
by: Takano, M, et al.
Published: (1994)

THE EFFECT OF INTRACELLULAR PROTONS ON ATP-SENSITIVE K+ CHANNELS IN MOUSE PANCREATIC BETA-CELLS
by: Proks, P, et al.
Published: (1993)

ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells.
by: Tarasov, A, et al.
Published: (2006)

Effects of intracellular pH on ATP-sensitive K+ channels in mouse pancreatic beta-cells.
by: Proks, P, et al.
Published: (1994)

THE EFFECT OF INTRACELLULAR PH ON ATP-SENSITIVE K+ CHANNELS IN ISOLATED MOUSE PANCREATIC BETA-CELLS
by: Proks, P, et al.
Published: (1993)

2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes
by: Julio Alvarez-Collazo, et al.
Published: (2016-12-01)

THE ROLE OF THE ATP-SENSITIVE K-CHANNEL IN STIMULUS-RESPONSE COUPLING IN THE PANCREATIC BETA-CELL
by: Ashcroft, S, et al.
Published: (1989)

ATP-sensitive K+ channels in rat pancreatic beta-cells: modulation by ATP and Mg2+ ions.
by: Ashcroft, F, et al.
Published: (1989)

Modification of K-ATP channels in pancreatic beta-cells by trypsin.
by: Proks, P, et al.
Published: (1993)

Gating and ATP-sensitivity of the cloned beta-cell K-ATP channel
by: Trapp, S, et al.
Published: (1998)

Rubidium and sodium permeability of the ATP-sensitive K+ channel in single rat pancreatic beta-cells.
by: Ashcroft, F, et al.
Published: (1989)

Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides.
by: Reimann, F, et al.
Published: (2003)

ATP-REGULATED K CHANNELS MODULATE ELECTRICAL-ACTIVITY IN MOUSE ISOLATED PANCREATIC BETA-CELLS
by: Ashcroft, F, et al.
Published: (1990)

Modulation of tolbutamide sensitivity of K-ATP currents in mouse pancreatic beta-cells by intracellular nucleotides and magnesium
by: Faehling, M, et al.
Published: (1996)

THE GLUCOSE-SENSITIVE POTASSIUM CHANNEL IN RAT PANCREATIC BETA-CELLS IS INHIBITED BY INTRACELLULAR ATP
by: Ashcroft, F, et al.
Published: (1985)

Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide.
by: Gribble, F, et al.
Published: (1999)

EFFECTS OF TRYPSIN ON ATP-DEPENDENT-K+ CHANNELS FROM PANCREATIC BETA-CELLS
by: Proks, P, et al.
Published: (1992)

The ATP- and tolbutamide-sensitivity of the ATP-sensitive K-channel from human pancreatic B cells.
by: Ashcroft, F, et al.
Published: (1989)

The dependence on intracellular ATP concentration of ATP-sensitive K-channels and of Na,K-ATPase in intact HIT-T15 beta-cells.
by: Niki, I, et al.
Published: (1989)

The ATP-sensitivity of K+ channels in rat pancreatic B-cells is modulated by ADP.
by: Kakei, M, et al.
Published: (1986)

RUBIDIUM ACTS AS A PERMEANT BLOCKER OF THE GLUCOSE AND ATP-SENSITIVE K-CHANNEL IN RAT PANCREATIC BETA-CELLS
by: Ashcroft, F, et al.
Published: (1986)

Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels.
by: Song, D, et al.
Published: (2001)

Properties and functions of ATP-sensitive K-channels.
by: Ashcroft, S, et al.
Published: (1990)

Dynamic sensitivity of ATP-sensitive K(+) channels to ATP.
by: Loussouarn, G, et al.
Published: (2001)

Dynamic sensitivity of K-ATP channels to ATP
by: Loussouarn, G, et al.
Published: (2001)

ATP-sensitive K+ channels in human isolated pancreatic B-cells.
by: Ashcroft, F, et al.
Published: (1987)

Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.
by: Ammälä, C, et al.
Published: (1991)

High-affinity block of K-ATP channels of mouse isolated pancreatic beta-cells but not rat heart or arterial smooth muscle cells by the sulphonylurea gliclazide
by: Jones, P, et al.
Published: (2001)

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells.
by: Bokvist, K, et al.
Published: (1991)

Block of ATP-regulated and Ca2(+)-activated K+ channels in mouse pancreatic beta-cells by external tetraethylammonium and quinine.
by: Bokvist, K, et al.
Published: (1990)

Differential metabolic and nucleotide sensitivity of beta-cell and cardiac K-ATP channels
by: Vedovato, N, et al.
Published: (2018)

A model for regulation of the beta-cell ATP-sensitive K+-channel by nucleotides and diazoxide.
by: Tucker, S, et al.
Published: (1997)

Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry
by: Usher, SG, et al.
Published: (2020)

EFFECTS OF MAGNESIUM-IONS ON ATP-SENSITIVE K-CHANNELS FROM RAT PANCREATIC B-CELLS
by: Ashcroft, F, et al.
Published: (1988)

ADP MODULATES THE ATP-SENSITIVITY OF THE K-CHANNEL CLOSED BY GLUCOSE IN ISOLATED RAT PANCREATIC B-CELLS
by: Ashcroft, F, et al.
Published: (1986)

Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.
by: Trapp, S, et al.
Published: (1998)

Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry
by: Samuel G Usher, et al.
Published: (2020-01-01)