Farnesyltransferase inhibitors as radiation sensitizers.

Farnesyltransferase inhibitors as radiation sensitizers.

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Activation of Ras, by mutation, overexpression, or by signaling through tyrosine kinase receptors, is associated with radioresistance. Thus, therapies that inhibit Ras function could be an effective means to radiosensitize selected types of solid tumors. Inhibition of Ras prenylation using a variety...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Mckenna, W, Muschel, R, Gupta, A, Hahn, S, Bernhard, E
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2002

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