Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

Expression of human leukocyte antigen (HLA)-B27 is strongly associated with predisposition toward ankylosing spondylitis (AS) and other spondyloarthropathies. However, the exact involvement of HLA-B27 in disease initiation and progression remains unclear. The homodimer theory, which proposes that HL...

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প্রধান লেখক: Lim Kam Sian, TCC, Indumathy, S, Halim, H, Greule, A, Cryle, MJ, Bowness, P, Rossjohn, J, Gras, S, Purcell, AW, Schittenhelm, RB
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: American Society for Biochemistry and Molecular Biology 2019

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