DNA repair capacity as a possible biomarker of breast cancer risk in female BRCA1 mutation carriers.

The BRCA1 gene product helps to maintain genomic integrity through its participation in the cellular response to DNA damage: specifically, the repair of double-stranded DNA breaks. An impaired cellular response to DNA damage is a plausible mechanism whereby BRCA1 mutation carriers are at increased r...

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Bibliografiska uppgifter
Huvudupphovsmän: Kotsopoulos, J, Chen, Z, Vallis, K, Poll, A, Ainsworth, P, Narod, SA
Materialtyp: Journal article
Språk:English
Publicerad: 2007