Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania
<p>People with HIV (PWH) have a >2-fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24-h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case-control study of ABPM in 137 PWH and HIV-uninfected c...
| Prif Awduron: | , , , , , , , , , |
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| Fformat: | Journal article |
| Iaith: | English |
| Cyhoeddwyd: |
Wiley
2021
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| _version_ | 1826310669339721728 |
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| author | Nolan, C Reis, K Fadhil, S Etyang, A Ezeomah, C Kingery, JR Desderius, B Lee, M-H Kapiga, S Peck, RN |
| author_facet | Nolan, C Reis, K Fadhil, S Etyang, A Ezeomah, C Kingery, JR Desderius, B Lee, M-H Kapiga, S Peck, RN |
| author_sort | Nolan, C |
| collection | OXFORD |
| description | <p>People with HIV (PWH) have a >2-fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24-h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case-control study of ABPM in 137 PWH and HIV-uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non-dipping of heart rate (HR) was significantly more common among PWH than HIV-uninfected controls (<em>p</em> = .01). Nocturnal non-dipping of BP was significantly more common in PWH with normal clinic BP (<em>p</em> = .048). Clinical correlates of nocturnal non-dipping were similar in PWH and HIV-uninfected adults and included higher BMI, higher CD4<sup>+</sup> cell count, and high C-reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non-dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference.</p> |
| first_indexed | 2024-03-07T07:56:51Z |
| format | Journal article |
| id | oxford-uuid:fca347c9-b2c3-4fea-a61c-166c36cd8bbd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:56:51Z |
| publishDate | 2021 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:fca347c9-b2c3-4fea-a61c-166c36cd8bbd2023-08-15T13:41:47ZNocturnal dipping of heart rate and blood pressure in people with HIV in TanzaniaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fca347c9-b2c3-4fea-a61c-166c36cd8bbdEnglishSymplectic ElementsWiley2021Nolan, CReis, KFadhil, SEtyang, AEzeomah, CKingery, JRDesderius, BLee, M-HKapiga, SPeck, RN<p>People with HIV (PWH) have a >2-fold greater risk for development of cardiovascular disease (CVD), which may be associated with abnormalities in 24-h ambulatory blood pressure measurement (ABPM) profile. We conducted a nested case-control study of ABPM in 137 PWH and HIV-uninfected controls with normal and high clinic blood pressure (BP) in Tanzania. Nocturnal non-dipping of heart rate (HR) was significantly more common among PWH than HIV-uninfected controls (<em>p</em> = .01). Nocturnal non-dipping of BP was significantly more common in PWH with normal clinic BP (<em>p</em> = .048). Clinical correlates of nocturnal non-dipping were similar in PWH and HIV-uninfected adults and included higher BMI, higher CD4<sup>+</sup> cell count, and high C-reactive protein for HR and markers of renal disease for BP. In conclusion, nocturnal non-dipping of both BP and HR was more common in PWH but further research is needed to determine causes and consequences of this difference.</p> |
| spellingShingle | Nolan, C Reis, K Fadhil, S Etyang, A Ezeomah, C Kingery, JR Desderius, B Lee, M-H Kapiga, S Peck, RN Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
| title | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
| title_full | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
| title_fullStr | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
| title_full_unstemmed | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
| title_short | Nocturnal dipping of heart rate and blood pressure in people with HIV in Tanzania |
| title_sort | nocturnal dipping of heart rate and blood pressure in people with hiv in tanzania |
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