Phenotypic diversity of the CD45 antigen and its relationship to function.

Monoclonal antibodies (mAbs) have identified further heterogeneity within the major CD4 and CD8 T-lymphocyte subsets. Antibodies to different polypeptides of the CD45 complex separate two largely non-overlapping subsets that may represent stages in the maturation of T cells or separate functionally...

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Bibliographic Details
Main Authors: Beverley, P, Merkenschlager, M, Terry, L
Format: Journal article
Language:English
Published: 1988
Description
Summary:Monoclonal antibodies (mAbs) have identified further heterogeneity within the major CD4 and CD8 T-lymphocyte subsets. Antibodies to different polypeptides of the CD45 complex separate two largely non-overlapping subsets that may represent stages in the maturation of T cells or separate functionally distinct subsets.