Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations

Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations

Glucose-1-phosphate uridylyltransferase in conjunction with UDP-glucose pyrophosphorylase was found to catalyse the conversion of a range of 5-substituted UTP derivatives into the corresponding UDP-galactose derivatives in poor yield. Notably the 5-iodo derivative was not converted to UDP-sugar. In...

书目详细资料
Main Authors:	Wagstaff, B, Rejzek, M, Pesnot, T, Tedaldi, L, Caputi, L, O’Neill, E, Benini, S, Wagner, G, Field, R
格式:	Journal article
出版:	Elsevier 2014

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