Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663.
Both the anticonvulsant and sedative effects of diazepam (5 mg/kg) were reversed by subsequent administration of the suggested specific benzodiazepine antagonist Ro 15-1788. In contrast neither the seizure threshold raising or sedative effect of melatonin (200 mg/kg) was reversed by Ro 15-1788. Ro 1...
Príomhchruthaitheoirí: | Green, A, Nutt, D, Cowen, P |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
Springer-Verlag
1982
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Míreanna comhchosúla
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