The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics
The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...
Main Authors: | Sankararamakrishnan, R, Adcock, C, Sansom, M |
---|---|
מחברים אחרים: | Biophysical Society |
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
Elsevier
1996
|
נושאים: |
פריטים דומים
-
Molecular dynamics study of water and Na⁺ ions in models of the pore region of the nicotinic acetylcholine receptor
מאת: Smith, G, et al.
יצא לאור: (1997) -
The dielectric properties of water within model transbilayer pores
מאת: Sansom, M, et al.
יצא לאור: (1997) -
Molecular dynamics simulations of water within models of ion channels
מאת: Breed, J, et al.
יצא לאור: (1996) -
The alpha7 nicotinic acetylcholine receptor: molecular modelling, electrostatics, and energetics.
מאת: Amiri, S, et al.
יצא לאור: (2005) -
The nicotinic acetylcholine receptor: from molecular model to single-channel conductance.
מאת: Adcock, C, et al.
יצא לאור: (2000)