The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics
The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...
主要な著者: | Sankararamakrishnan, R, Adcock, C, Sansom, M |
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その他の著者: | Biophysical Society |
フォーマット: | Journal article |
言語: | English |
出版事項: |
Elsevier
1996
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主題: |
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