The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics

The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...

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Bibliografiske detaljer
Main Authors: Sankararamakrishnan, R, Adcock, C, Sansom, M
Andre forfattere: Biophysical Society
Format: Journal article
Sprog:English
Udgivet: Elsevier 1996
Fag: