The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics

The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...

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Príomhchruthaitheoirí: Sankararamakrishnan, R, Adcock, C, Sansom, M
Rannpháirtithe: Biophysical Society
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Elsevier 1996
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