The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics

The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...

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Những tác giả chính: Sankararamakrishnan, R, Adcock, C, Sansom, M
Tác giả khác: Biophysical Society
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Elsevier 1996
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