Mitotic recombination of yeast artificial chromosomes.

Large regions of human DNA can be cloned and mapped in yeast artificial chromosomes (YACs). Overlapping YAC clones can be used in order to reconstruct genomic segments in vivo by meiotic recombination. This is of importance for reconstruction of a long gene or a gene complex. In this work we have ta...

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Detalhes bibliográficos
Main Authors: Ragoussis, I, Trowsdale, J, Markie, D
Formato: Journal article
Idioma:English
Publicado em: 1992