Downstage migration after neoadjuvant chemoradiotherapy for rectal cancer: the reverse of the Will Rogers phenomenon?

Downstaging after neoadjuvant treatment is increasingly used as a prognostic factor and surrogate endpoint in clinical trials. However, in recent trials of neoadjuvant 5-fluorouracil-based chemoradiotherapy for rectal cancer, downstaging did not translate into a benefit with regard to either disease...

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Bibliographic Details
Main Authors: Fokas, E, Liersch, T, Fietkau, R, Hohenberger, W, Hess, C, Becker, H, Sauer, R, Wittekind, C, Rödel, C
Format: Journal article
Language:English
Published: Wiley 2015

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