Conditional genealogies and the age of a neutral mutant.
This paper is concerned with the structure of the genealogy of a sample in which it is observed that some subset of chromosomes carries a particular mutation, assumed to have arisen uniquely in the history of the population. A rigorous theoretical study of this conditional genealogy is given using c...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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1999
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| _version_ | 1826306749592764416 |
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| author | Wiuf, C Donnelly, P |
| author_facet | Wiuf, C Donnelly, P |
| author_sort | Wiuf, C |
| collection | OXFORD |
| description | This paper is concerned with the structure of the genealogy of a sample in which it is observed that some subset of chromosomes carries a particular mutation, assumed to have arisen uniquely in the history of the population. A rigorous theoretical study of this conditional genealogy is given using coalescent methods. Particular results include the mean, variance, and density of the age of the mutation conditional on its frequency in the sample. Most of the development relates to populations of constant size, but we discuss the extension to populations which have grown exponentially to their present size. |
| first_indexed | 2024-03-07T06:52:39Z |
| format | Journal article |
| id | oxford-uuid:fd0daa37-6cde-42a1-8d04-60eaef3df82b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:52:39Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:fd0daa37-6cde-42a1-8d04-60eaef3df82b2022-03-27T13:25:55ZConditional genealogies and the age of a neutral mutant.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fd0daa37-6cde-42a1-8d04-60eaef3df82bEnglishSymplectic Elements at Oxford1999Wiuf, CDonnelly, PThis paper is concerned with the structure of the genealogy of a sample in which it is observed that some subset of chromosomes carries a particular mutation, assumed to have arisen uniquely in the history of the population. A rigorous theoretical study of this conditional genealogy is given using coalescent methods. Particular results include the mean, variance, and density of the age of the mutation conditional on its frequency in the sample. Most of the development relates to populations of constant size, but we discuss the extension to populations which have grown exponentially to their present size. |
| spellingShingle | Wiuf, C Donnelly, P Conditional genealogies and the age of a neutral mutant. |
| title | Conditional genealogies and the age of a neutral mutant. |
| title_full | Conditional genealogies and the age of a neutral mutant. |
| title_fullStr | Conditional genealogies and the age of a neutral mutant. |
| title_full_unstemmed | Conditional genealogies and the age of a neutral mutant. |
| title_short | Conditional genealogies and the age of a neutral mutant. |
| title_sort | conditional genealogies and the age of a neutral mutant |
| work_keys_str_mv | AT wiufc conditionalgenealogiesandtheageofaneutralmutant AT donnellyp conditionalgenealogiesandtheageofaneutralmutant |